CAS 9050‐31‐1

Nulose HP

Hydroxypropyl Methyl Cellulose Phthalate (HPMC‐P)

Nulose HP is an excellent enteric coating material. Other applications are for the sustained-release material of tablets, capsule adhesive, microencapsulation substrate, implants, taste masking agent, microspheres, oral membranes, and solid dispersion. The release rate is based on he pH value.

Technical Specification

Complies with USP/NF and EP

Preparation for Coating Solution

Organic solvents for HPMC-P :
Acetone:Water = 9:1
Methylene Chloride Ethanol = 1:1
Acetone:Ethanol = 1:1
Ethanol:Water = 8:2 (Solution temperature above 25°C)
Methylene Chloride:Ethanol:Water = 5:4:1

Dissolving method

Add the suggested amount of solvent while slowly stirring, add HPMC-P and stir until desired viscosity.


25 kg polyethylene bag in a fiber drum.